"The Long Run" Antarctic explorer Ernest Shackleton would appreciate today's biotech. Scientific entrepreneurs of the 21st century must be ready for what Shackleton called the “hazardous journey, bitter cold, long months of complete darkness, constant danger, safe return doubtful, honor and recognition in case of success.” Today, the men and women who strive to apply science for the betterment of human health have a historic opportunity. They need stamina and resilience to achieve something ...
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Ep173: Robert Blum on Building a Fully Integrated Biopharma For Muscle Disorders
57:56
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57:56Robert Blum, CEO of South San Francisco-based Cytokinetics, on building a fully integrated biopharma to treat muscle disorders.De către Timmerman Report
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Ep172: Mostafa Ronaghi on Studying Live Cells at Scale
1:20:53
1:20:53
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1:20:53Mostafa Ronaghi, co-founder and executive board member of Cellanome, on developing technology to look at live cells and cellular interactions at scale.De către Timmerman Report
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Ep171: Ram Aiyar on RNA Editing Medicines
1:01:48
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1:01:48Ram Aiyar, CEO of Cambridge, Mass.-based Korro Bio, on RNA editing medicines.De către Timmerman Report
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Ep170: David Schenkein on Investing in the Future of Biotech
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59:52David Schenkein, general partner at GV, on investing in the future of biotech.De către Timmerman Report
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Ep169: Kevin Fitzgerald on the Past & Future of RNAi Medicines
1:02:28
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1:02:28Alnylam Pharmaceuticals chief scientific officer Kevin Fitzgerald on the past, present & future of RNA interference medicines.De către Timmerman Report
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Ep168: Jonathan Bricker on How to Quit Smoking & Prevent Cancer
1:00:23
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1:00:23Jonathan Bricker, professor in the cancer prevention program at Fred Hutchinson Cancer Center, on how to quit smoking with help from tech and biotech tools.De către Timmerman Report
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Ep167: Leslie Williams on transfer RNA therapies
1:11:28
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1:11:28Leslie Williams, CEO of Boston-based hC Bioscience, on developing transfer RNA therapies.De către Timmerman Report
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Ep166: Chris Garcia on Engineering Protein Drugs for Cancer, Autoimmunity
1:03:35
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1:03:35Chris Garcia, professor at Stanford University and co-founder of several biotech startups, on using protein engineering to advance new treatments for cancer and autoimmune diseases.De către Timmerman Report
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Ep165: Zach Hornby on Tackling Cancer Drug Resistance
1:02:45
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1:02:45Zach Hornby, CEO of San Diego-based Boundless Bio, on tackling cancer drug resistance.De către Timmerman Report
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Ep164: Ted Love and Alan Anderson on Raising the Bar for Sickle Cell Disease Patients
56:39
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56:39Ted Love, chairman of BIO, and Dr. Alan Anderson, executive director of Sickle Forward, on how to improve quality of life for sickle cell disease patients around the world.De către Timmerman Report
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Ep163: Sarah Boyce on RNA Medicines for Muscle Diseases
1:08:19
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1:08:19Sarah Boyce, CEO of San Diego-based Avidity Biosciences, on RNA medicines for rare muscle diseases.De către Timmerman Report
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Ep162: Sean McClain on AI for Biologic Drug Discovery
1:05:59
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1:05:59Sean McClain, CEO of Absci, on using AI to speed up biologic drug discovery.De către Timmerman Report
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Ep161: Jeff Stein on a Long-Lasting Flu Drug
1:08:51
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1:08:51Jeff Stein, CEO of San Diego-based Cidara Therapeutics, on a long-lasting drug against flu.De către Timmerman Report
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Ep160: Abe Ceesay on Precision Neuroscience
1:08:48
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1:08:48Abe Ceesay, CEO of Boston-based Rapport Therapeutics, on a precision medicine approach to neuroscience drug discovery.De către Timmerman Report
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Ep159: Jimi Olaghere on Being Functionally Cured of Sickle Cell Disease
1:07:22
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1:07:22Jimi Olaghere is one of the first patients to have been functionally cured of sickle cell disease with a CRISPR gene-edited cell therapy.De către Timmerman Report
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Ep158: David Younger and Randolph Lopez on SynBio & AI for Discovery
1:00:44
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1:00:44David Younger and Randolph Lopez, co-founders of A-Alpha Bio, on using synthetic biology and AI to discover new biologic drugs.De către Timmerman Report
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Ep157: Vineeta Agarwala of A16Z on Investing in AI for Drug Discovery
56:33
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56:33Vineeta Agarwala, general partner at A16Z's Bio & Health fund, on investing in AI for drug discovery.De către Timmerman Report
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Ep156: David Liu on New Tools and Techniques for Biology
1:52:57
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1:52:57David Liu, professor of chemistry at Harvard University and co-founder of multiple biotech companies, including Beam Therapeutics and Prime Medicine.De către Timmerman Report
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Ep155: Valerie Daggett on Early Detection, and Treatment, of Alzheimer's
1:02:37
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1:02:37Valerie Daggett, founder and CEO of Seattle-based AltPep, on early detection and treatment of Alzheimer's.De către Timmerman Report
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Ep154: Robert Ang on CRISPR to Protect Bone Marrow & Attack Cancer
1:03:14
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1:03:14Robert Ang, CEO of Cambridge, Mass.-based Vor Bio, on using CRISPR gene editing to alter bone marrow transplants and improve treatment of acute myeloid leukemia.De către Timmerman Report
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Ep153: Rick Young on Studying Gene Expression for Drug Discovery
1:01:43
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1:01:43Rick Young, professor at MIT and co-founder of Syros Pharmaceuticals, CAMP4 Therapeutics, Omega Therapeutics, and Dewpoint Therapeutics, on studying gene expression for drug discovery.De către Timmerman Report
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Ep152: Jens Eckstein on Investing in Healthy Aging
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1:05:05Jens Eckstein, investment partner at Hevolution Foundation, on investing in healthy aging.De către Timmerman Report
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Ep151: Shelley Force Aldred and Nathan Trinklein on Bispecific Antibodies for Cancer
1:03:55
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1:03:55Shelley Force Aldred and Nathan Trinklein, co-founders of Rondo Therapeutics, on the opportunity with bispecific antibodies for cancer.De către Timmerman Report
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Ep150: Jeff Jonker on the Small Molecule Drug Discovery Renaissance
1:03:48
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1:03:48Jeff Jonker, CEO of San Diego-based Belharra Therapeutics, on the renaissance in small molecule drug discovery.De către Timmerman Report
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Ep149: Nancy Stagliano on Precision Neuroscience
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1:01:53Nancy Stagliano, CEO of South San Francisco-based Neuron23, on bringing precision medicine to neuroscience drug discovery.De către Timmerman Report
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Ep148: Diana Brainard on the Fight Against Infectious Disease
1:03:27
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1:03:27Diana Brainard, CEO of AlloVir, on leading the fight against infectious diseases.De către Timmerman Report
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Ep147: Reid Huber on Investing in the Future of Medicine
1:08:41
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1:08:41Reid Huber, partner at Third Rock Ventures, on investing in the future of medicine.De către Timmerman Report
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Ep146: Jeff Huber on Life in Tech and Biotech
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1:47:05Jeff Huber, co-founder and general partner at Triatomic Capital, on his career path in tech, and then biotech.De către Timmerman Report
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Ep145: Lori Lyons-Williams on Targeted Radiopharmaceuticals for Cancer
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1:06:39Lori Lyons-Williams, CEO of Abdera Therapeutics, on developing targeted radiopharmaceuticals for cancer.De către Timmerman Report
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Ep144: Turning the Tables, Rob Perez Interviews Me
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1:04:58Turning the Tables, Rob Perez Interviews MeDe către Timmerman Report
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Ep143: Zach Weinberg and Alexis Borisy on Freeing the Biotech Founders
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1:10:25Zach Weinberg and Alexis Borisy of Curie.Bio on Freeing the Biotech FoundersDe către Timmerman Report
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Ep142: Fred Appelbaum on how 'Living Medicine' Came to Be
55:54
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55:54Fred Appelbaum, a physician, scientist and leader at the Fred Hutchinson Cancer Center, on 'Living Medicine,' his new book about the development of bone marrow transplantation and the rise of cell therapy.De către Timmerman Report
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Ep141: Colin Hill on Digging Deep into Data, Finding New Drug Targets
1:09:30
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1:09:30Colin Hill, co-founder and CEO of Aitia, on digging deep into biological datasets and finding new drug targets.De către Timmerman Report
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Ep140: Yung Lie on Supporting Young Scientists with Bold, Brave Ideas
1:02:40
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1:02:40Yung Lie, president and CEO of Damon Runyon Cancer Research Foundation, on advancing cancer research by supporting young scientists with bold and brave ideas.De către Timmerman Report
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Ep139: Kevin Conroy on Early Detection of Cancer
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1:08:28Kevin Conroy, CEO of Exact Sciences, on early detection of cancer.De către Timmerman Report
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Ep138: Jodie Morrison on Becoming a Biotech CEO
1:00:17
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1:00:17Jodie Morrison, acting CEO of Q32Bio, on becoming a biotech CEO.De către Timmerman Report
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Ep137: Aaron Ring on Immunotherapy for Cancer & More
56:37
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56:37Aaron Ring, a scientist at Yale moving to the Fred Hutchinson Cancer Center, on applying immunology and protein engineering for cancer therapy and more.De către Timmerman Report
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Ep136: Deborah Palestrant on Building Biotech Startups
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52:52Deborah Palestrant, partner at 5AM Ventures and head of the 4:59 initiative, on building biotech startups.De către Timmerman Report
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Ep135: John Maraganore on Developing a New Class of Medicines
1:03:51
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1:03:51John Maraganore, former founding CEO of Alnylam Pharmaceuticals, on his life in biotech and developing RNA interference as a new class of medicine.De către Timmerman Report
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Ep134: Emile Nuwaysir on In Vivo Gene Editing Therapies
1:16:22
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1:16:22Emile Nuwaysir, CEO of Boston-based Ensoma, on developing off-the-shelf in vivo gene editing therapies.De către Timmerman Report
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Ep133: Catherine Stehman-Breen on Epigenetic Editing Therapies
1:10:33
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1:10:33Catherine Stehman-Breen, CEO of Boston-based Chroma Medicine, on developing epigenetic editing therapies.De către Timmerman Report
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Ep132: Eric Dobmeier on Treating Kidney Disease
1:05:44
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1:05:44Eric Dobmeier, CEO of Seattle-based Chinook Therapeutics, on new strategies for treating kidney diseases.De către Timmerman Report
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Ep131: Ryan Watts on Neuroscience Drug R&D
1:05:32
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1:05:32Ryan Watts, CEO of South San Francisco-based Denali Therapeutics, on neuroscience drug discovery and development.De către Timmerman Report
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Ep130: David Hallal on a Life in Biotech & the Cell Therapy Wave
1:09:29
1:09:29
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1:09:29David Hallal, CEO of ElevateBio, on a long career in biotech and the coming 50-year opportunity in cell therapy and gene therapy.De către Timmerman Report
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Ep129: Joanne Smith-Farrell on Engineered B-Cell Therapies
1:11:43
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1:11:43Joanne Smith-Farrell, CEO of Cambridge, Mass.-based Be Biopharma, on Engineered B-Cell Therapies for Cancer & Rare Diseases.De către Timmerman Report
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Ep128: Rick Berke on Building a Biotech Journalism Outlet to Last
1:00:34
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1:00:34Rick Berke, co-founder and executive editor of STAT, on building a biotech journalism outlet to last.De către Timmerman Report
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Ep127: Jeb Keiper on Computational Drug Discovery
1:09:41
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1:09:41Jeb Keiper, CEO of Nimbus Therapeutics, on computational drug discovery, an unusual business model, and an important new Tyk2 inhibitor for psoriasis and other forms of autoimmunity.De către Timmerman Report
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Ep126: DA Wallach on Becoming a Biotech VC
1:11:38
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1:11:38DA Wallach, founder and general partner of TIME Bioventures, on becoming a biotech venture investor.De către Timmerman Report
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Ep125: Barry Greene on a New Drug for Depression
1:04:52
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1:04:52Barry Greene, CEO of Cambridge, Mass.-based Sage Therapeutics, on plans to introduce a new type of treatment for depression and postpartum depression.De către Timmerman Report
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Ep124: Shehnaaz Suliman on Delivery of Genetic Medicines
1:09:53
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1:09:53Shehnaaz Suliman, CEO of ReCode Therapeutics, on lipid nanoparticle delivery of genetic medicines.De către Timmerman Report
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