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63. Protein Dysregulation in Neurodegenerative Disorders (with Dr. Estella Newcombe)
Manage episode 384111454 series 3412534
Content provided by Neuroverse. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Neuroverse or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ro.player.fm/legal.
In this episode, we are joined by a special guest, Dr. Estella Newcombe, to discuss protein dysregulation in neurodegenerative disorders.
Estella is currently a Marie Sklodowska-Curie Fellow at the University of Copenhagen in the structural biology and NMR laboratory, researching intrinsically disordered proteins in the context of neurodegenerative disorders. Estella holds a Bachelor’s degree in Biotechnology and Chemistry from the University of Queensland and a PhD in Biochemistry and Molecular Biology from the University of Melbourne, where she studied the interactions and structures of proteins in Huntington’s disease. She subsequently worked as a postdoctoral fellow at the Queensland Brain Institute studying the structures of intrinsically disordered proteins. Based on her wide range of experience in the fields of structural protein biology and neuroscience, in this episode we discuss the value of studying human neurodegenerative disorders at the level of protein-protein interactions. We cover what intrinsically disordered proteins are, the relevance of structure-function relationships, and how environmental factors influence protein dysfunction in neurodegeneration.
---
We hope you enjoy the episode! Please feel free to share with your friends and family, it means a lot to us🤍
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87 episoade
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Manage episode 384111454 series 3412534
Content provided by Neuroverse. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Neuroverse or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ro.player.fm/legal.
In this episode, we are joined by a special guest, Dr. Estella Newcombe, to discuss protein dysregulation in neurodegenerative disorders.
Estella is currently a Marie Sklodowska-Curie Fellow at the University of Copenhagen in the structural biology and NMR laboratory, researching intrinsically disordered proteins in the context of neurodegenerative disorders. Estella holds a Bachelor’s degree in Biotechnology and Chemistry from the University of Queensland and a PhD in Biochemistry and Molecular Biology from the University of Melbourne, where she studied the interactions and structures of proteins in Huntington’s disease. She subsequently worked as a postdoctoral fellow at the Queensland Brain Institute studying the structures of intrinsically disordered proteins. Based on her wide range of experience in the fields of structural protein biology and neuroscience, in this episode we discuss the value of studying human neurodegenerative disorders at the level of protein-protein interactions. We cover what intrinsically disordered proteins are, the relevance of structure-function relationships, and how environmental factors influence protein dysfunction in neurodegeneration.
---
We hope you enjoy the episode! Please feel free to share with your friends and family, it means a lot to us🤍
Neuroverse Website
https://neuroversepod.com
Podcast directory
https://anchor.fm/neuroverse9
Support us!
https://ko-fi.com/neuroverse
Twitter: @neuroverse_pod
https://twitter.com/neuroverse_pod?s=21&t=KvAEuwGNKFQ9IPKlL7NTEg
Instagram: @Neuroverse_pod
https://instagram.com/neuroverse_pod?igshid=YmMyMTA2M2Y=
Help us improve our podcast by giving us some feedback!
87 episoade
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Similar cu Neuroverse
Get in-depth coverage of current and future trends in technology, and how they are shaping business, entertainment, communications, science, politics, and society.
…
continue reading
Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
Artificial Intelligence has suddenly gone from the fringes of science to being everywhere. So how did we get here? And where's this all heading? In this new series of Science Friction, we're finding out.
…
continue reading
Come dive into one of the curiously delightful conversations overheard at National Geographic’s headquarters, as we follow explorers, photographers, and scientists to the edges of our big, weird, beautiful world. Hosted by Peter Gwin and Amy Briggs.
…
continue reading
DNA science. Artificial intelligence. Smartphones and 3D printers. Science and technology have transformed the world we live in. But how did we get here? It wasn’t by accident. Well, sometimes it was. It was also the result of hard work, teamwork, and competition. And incredibly surprising moments. Hosted by bestselling author Steven Johnson (“How We Got To Now”), American Innovations uses immersive scenes to tell the stories of the scientists, engineers, and ordinary people behind the great ...
…
continue reading
Join Dr Karl Kruszelnicki, Lucy Smith and their scientific guests, with a bunch of curious triple j listeners for a weekly injection of science, myth-bashing and answers!
…
continue reading
We humans could have a bright future ahead of us that lasts billions of years. But we have to survive the next 200 years first. Join Josh Clark of Stuff You Should Know for a 10-episode deep dive that explores the future of humanity and finds dangers we have never encountered before lurking just ahead. And if we humans are alone in the universe, if we don't survive intelligent life dies out with us too.
…
continue reading
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…
continue reading
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…
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Whether we wear a lab coat or haven't seen a test tube since grade school, science is shaping all of our lives. And that means we all have science stories to tell. Every year, we host dozens of live shows all over the country, featuring all kinds of storytellers - researchers, doctors, and engineers of course, but also patients, poets, comedians, cops, and more. Some of our stories are heartbreaking, others are hilarious, but they're all true and all very personal. Welcome to The Story Collider!
…
continue reading
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