Cele mai bune Brrrrr podcast-uri (2024)

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Episode 16 - Brrrrr-eaking it down | Cold Haemolysis & Cryoglobulins 38:33

4d ago38:33

38:33

Grab your hot beverage of choice and come out of the cold as we give you a warm welcome to the world of cold-dependent antibodies! No need to cry(o) as we unpack CAD vs CAS, get personal with PCH and gaze without alliteration at whatever the hell cryoglobulins are. If you're desperate for a medical reason to move to the tropics, this is the episode…

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Episode 15 - Antibodies behaving badly | Warm Autoimmune Haemolysis 29:32

11d ago29:32

29:32

Is there a glow surrounding your red cells? Things feeling heated in your reticuloendothelial system? An antibody to keep your bed warm at night? We don’t know where this is going either but grab a coconut and hop in the pool because we are excited to welcome you back with a chat about warm autoimmune haemolysis! Timestamps 00:57 - Introduction & C…

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Episode 14 - Throwing Frags | Introduction to MAHA 24:39

18d ago24:39

24:39

Feel your knowledge fragmenting? A MAHA doesn't make you haha? I mean, that's probably a good thing - they're quite serious. Time to unpack the troublesome schistocytes. Hope you brought your helmets as we teach you the bare minimum about fragments so you can save lives on the ward. Timestamps 02:26 - What is a red cell fragment? 06:09 - How are sc…

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Episode 13 - In the Lab: Dr Coombs? Who is DAT? | Direct Coombs Test 30:47

25d ago30:47

30:47

“It’s Test. Coombs Test. And I like my erythrocytes shaken, not stirred.” Return the lab (where some of the Bloody Minded Crew truly belong) and uncover the secrets of the most important test in haemolysis - the Direct Antiglobulin Test. Learn to whisper its secrets and it can guide you to identifying the true culprit behind these broken red cells.…

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Episode 12 - Haemolysis: Breaking it down! | Testing for Haemolysis 28:51

1M ago28:51

28:51

Haemolysis? Do I really hapto send off more tests? This is reticulous! Now you know what a red cell is - lets learn about how they can break down. Join us as we explore what your boss actually wanted you to do when they asked for a haemolysis screen, and about Cale's deep seated distrust of hepatologists. Timestamps 2:30 - Haemolysis - what is it (…

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Episode 11 - What is Blood ft. Erythrocytes | Haematopoiesis & Haematinics Overview 27:06

1M ago27:06

27:06

What is blood (Baby don't hurt me)? Rejoice as we escape the land of coagulation and look at some of the questions we have all asked during our medical training- what is blood? Does everybody have blood? Why is there so much of it on this floor? Who are you and how did you get in here? Join us as we we answer all these questions and more this episo…

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Episode 10 - Snakes on the (Clinical) Brain | Venoms in Clinical Use 35:21

2M ago35:21

35:21

Echis carinatus, Daboia russelii, Uxyuranus scullatellas. Never has so much been owed by so many humans to so few... snakes. In this split episode, For the first time the Bloody Minded Crew is delighted to welcome guests! Join our coagulation experts Dr Maeve Crowley and Kent Chapman for a tour of the wonderful world of exotic clotting times. This …

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Episode 9 - Snakes on the (Laboratory) Brain | Venoms in the Coagulation Lab 36:02

2M ago36:02

36:02

Echis carinatus, Daboia russelii, Uxyuranus scullatellas. Never has so much been owed by so many humans to so few... snakes. For the first time the Bloody Minded Crew is delighted to welcome guests! Join consultant haematologist Dr Maeve Crowley and senior hospital scientist Kent Chapman for a tour of the wonderful world of exotic clotting times. T…

1
Episode 8 - In the Lab: The Bethesda Assay 21:55

2M ago21:55

21:55

The Bethesda Assay has been tormenting haematology trainees since well before Fallout or Skyrim. Uncover its secrets in this episode and you'll be sorting acquired haemophilia faster than you can say Fus Ro Dah Timestamps: 01:50 - Bethesda Assay Intro 05:17 - How it works (and Bethesda Units) 10:25 - Nijmegen modification & dealing with Emicizumab …

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Episode 7 - In the Lab: Factor Assays 34:08

3M ago34:08

34:08

One step, two step, red step, blue step! Get stuck in to assessing factor levels in this episode looking at the differences between one and two step factor assays, the basis of chromogenic testing and how to resolve discrepancies between different methods. Timestamps: 01:33 Intro to Factor Assays 04:33 One-Stage Assays 09:33 Historical Diversion - …

1
Episode 6 - In the Lab: Lupus Anticoagulants 33:29

3M ago33:29

33:29

Finding your coagulation knowledge "LAC-ing"? Do you also hate things that were named terribly and thrive on pedantry? This week we pop the hood on that most mysterious of lab tests - the lupus anticoagulant. Listen to this episode again in 12 weeks time for an authentic lupus anticoagulant experience. Timestamps: 02:10 - Introducing the LAC 04:47 …

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Episode 5 - In the Lab: Thrombin Time, Fibrinogen and Anti-Xa assays 36:12

3M ago36:12

36:12

To infinXa and beyond! Let go of your veXation and eXalt our eXacting approach to coagulation testing. You'll know eXactly what you need for your eXams as long as they ask you about anti-Xa testing, thrombin times, fibrinogen and absolutely nothing else. Timestamps 0:00 - Introductions 2:40 - Thombin Time - Lab 5:45 - Thrombin Time - Clinical 9:24 …

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Episode 4 - Forever Alone: The Isolated Prolonged aPTT 26:31

3M ago26:31

26:31

Being alone can be difficult - and we would know! How should we think about a long aPTT when the rest of the coag screen looks normal? Join Bloody Minded crew as we learn how to tackle this surprisingly common (and surprisingly tricky) problem. Timestamps 00:00 - Introductions 02:21 - aPTT Revision 03:59 - A case 08:04 - Testing for heparins 10:10 …

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Episode 3 - Waiting for Clot(-o) | Prolonged Clotting Times and Anticoagulants 47:17

4M ago47:17

47:17

“Have you not done tormenting me with your accursed time?“ Senior scientists Vladimir and Estragon are waiting quite a while for a clot to form in their tube. How should you react to prolonged clotting times? We cover an approach to prolonged PT and aPTT, as well as discuss the mechanism of common anticoagulants and their impact on these basic test…

1
Episode 2 - In the Lab: PT and aPTT 29:13

4M ago29:13

29:13

It is a truth universally acknowledged that a JMO in possession of a coagulation tube will underfill it. But why should it matter?! In this episode, we review the principles behind the two most important coagulation screening tests (The PT and the aPTT) as well as follow the journey of that precious citrated sample through the lab. By the end, you’…

1
Episode 1 - Crafting a Clot | Coagulation Cascade Overview 31:35

4M ago31:35

31:35

Surely it's just clot or no clot right? Join your intrepid guides Nick, Cale and Bashar as we help you master the med school coagulation cascade and its relevance (or lack of) to laboratory testing of haemostasis. Wait what’s that? Everything you’ve been taught so far is an irrelevant lie? Bring yourself up to speed with the cellular model of coagu…

1
Episode 0 - Introductions 4:36

4M ago4:36

4:36

Optional Introductions - Skip to Episode 1 if you're after content We're excited to launch Bloody Minded - a haematology podcast for those who want an extra little drop of knowledge no matter where you are in your medical journey. Learn a little bit about your hosts and how we'll be formatting this show Check out show notes, additional references a…

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08 Eddie Wilson 42:47

1+ y ago42:47

42:47

Eddie Wilson Christian Media International Think Realty Eddie's proprietary operating system Empire Great Products you should go buy ;) Because Coffee Dirty Dough Book Recommendations Time-Wealth-Purpose Nothing Down, How to buy Real Estate with Little or No Money Down Awareness: The Perils and Opportunities of Reality Rich Dad Poor Dad…

1
LLMs eat software development 2:04:02

1+ y ago2:04:02

2:04:02

LLMs for software development can go way beyond Github Copilot. In this episode, we talk about how these models could change the workflow for existing developers, but more importantly how they could change the very idea of what software is. Links/Resources: https://simonwillison.net/2023/Mar/11/llama/ https://github.com/RootbeerComputer/backend-GPT…

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07 Tego Venturi 50:02

1+ y ago50:02

50:02

https://linktr.ee/empowergood Books https://www.amazon.com/Exactly-What-Say-Influence-Impact-ebook/dp/B073SF65ZZ https://www.amazon.com/Young-Forever-Secrets-Longest-Healthiest/dp/0316453188/ref=sr_1_1?hvadid=622788509420&hvdev=c&hvlocphy=1026339&hvnetw=g&hvqmt=e&hvrand=6076818953131565874&hvtargid=kwd-1762206633577&hydadcr=14935_13423621&keywords=…

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Dependent Types: Runtime assertions at compile time...whaaa? (S04E08) 2:07:07

1+ y ago2:07:07

2:07:07

Dependent types are a more expressive type system in programming languages used to catch a larger class of errors at compile time. What are would be typically assertions at runtime can now be caught at compile time. Show notes: Proposition as Types Parse, Don’t Validation “Scala vs Idris: Dependent types, now and in the future” Resources: http://ww…

1
06 Intro to the infamous BRRRR strategy 12:20

1+ y ago12:20

12:20

We will be going much further in depth with you on actual BRRRR projects in the future, but here is your intro to this great strategy to keep in your tool bag as one more way to GROW wealth and EMPOWER good! https://linktr.ee/empowergoodDe către Dave Parton

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05 Empower Good ~ GOALS 100,000 kids 13:56

1+ y ago13:56

13:56

We CAN adopt 100,000 kids and this is how. https://linktr.ee/empowergoodDe către Dave Parton

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04 Empower Good - What does that even mean? 14:19

1+ y ago14:19

14:19

Who are we and why do we use the Empower Good handle? We believe that if generous people are able to leverage their assets for additional time and money that they will be MORE generous. Real estate investing for the purpose of giving back helps YOU to do what other people won't so that you CAN help where other people can't. https://linktr.ee/empowe…

1
03 Wendy and Brandon 1:05:25

1+ y ago1:05:25

1:05:25

Come see me Wendy and Brandon Insta The E-myth Contractor Who Not How The Book on Managing Rental Properties The Richest Man in Babylon Please consider supporting Misspits Rescue Mini storage HERE and HERE Work with Brandon on your next flip!De către Dave Parton

1
02 Getting Started (house #1) 19:56

1+ y ago19:56

19:56

I will be sharing how Julia and I got started in real estate by telling you the good and bad about our first several purchases. Come see meDe către Dave Parton

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ActivityPub: A Pu Pu Platter of Internet Content (S04E07) 1:48:09

1+ y ago1:48:09

1:48:09

Activity Pub is a decentralized social networking protocol. It allows different web applications to interact so that their users can share information, even if the websites or applications are running different software. 00:00 S04E07 Activitypub 02:13 What is Activity Pub? 15:02 Interoperability 33:00 A New Kind of Social 43:53 Providing Distributi…

1
01 Cody and Christian saved this train wreck episode 25:47

1+ y ago25:47

25:47

Cody and Christian, guest...? host...? ghost...? walk us through deals, strategy, what matters to them in the Empower Good space, and even manage to save the Podcast when my phone overheated and I lost service multiple times. Facepalm. Thanks guys! Book recommendations from this episode: The Closer's Survival Guide The 10 X Rule Deals on Wheels Fin…

1
Episode intro 0:37

1+ y ago0:37

0:37

Not an episode!De către Dave Parton

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APL: You need a special keyboard to program in this language (S04E06) 1:42:29

1+ y ago1:42:29

1:42:29

APL is an array based programming language developed by Kenneth Iverson in the 1960s. Its central data type is the multi-dimensional array and hence it's very useful for workloads involving a lot of matrix math. APL predominantly uses symbols and it leverages consistent composability and execution rules to enable it as a notation as a tool for thou…

1
io_uring: Two rings makes computers go Brrrrr (S04E05) 1:27:51

1+ y ago1:27:51

1:27:51

io_uring is a new asynchronous, API to enable fast and efficient system calls in the Linux kernel. It promises faster user-land programs that heavily use file system IO on Linux, for all applications, not just databases. 00:00 S04 E05 io_uring 02:55 What is io_uring? 05:59 What's wrong with existing async interfaces? 17:25 Copying is slow 19:05 Two…

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Xanadu: The lost vision of the hypertext future (S04E04) 1:46:00

1+ y ago1:46:00

1:46:00

Xanadu was the first hypertext project founded in 1960 by Ted Nelson. It aims to facilitate a type of media called hypermedia, which is non-sequential writing in which the reader can choose their own path through an electronic document. Links/Resources: http://www.rheingold.com/texts/tft/14.html https://en.wikipedia.org/wiki/Project_Xanadu https://…

1
ChatGPT Part 2 (S04E03) 1:49:46

1+ y ago1:49:46

1:49:46

ChatGPT is a language model by OpenAI which interacts in a conversational way. The dialogue format makes it possible for ChatGPT to answer followup questions, admit its mistakes, challenge incorrect premises, and reject inappropriate requests. 00:00 S04E03 ChatGPT Part 2 02:30 Expanding Humanity's Limits 11:33 Tool-assisted speedrun of Science 16:1…

1
ChatGPT Part 1 (S04E03) 1:30:24

1+ y ago1:30:24

1:30:24

ChatGPT is a language model by OpenAI which interacts in a conversational way. The dialogue format makes it possible for ChatGPT to answer followup questions, admit its mistakes, challenge incorrect premises, and reject inappropriate requests. 00:00 S04E03 ChatGPT Part 1 02:58 What is ChatGPT? 06:17 Lineage of ChatGPT 10:01 General Reasoning from T…

1
Nix Package Management (S04E02) 1:35:08

1+ y ago1:35:08

1:35:08

Nix is a functional package manager. It creates completely reproducible builds and package management, including support for multiple versions of packages side-by-size with no issues. Chapters: [00:00:00] Intro [00:02:41] What is Nix? [00:05:01] The Problem with Package Management [00:09:41] How Nix Works [00:15:08] Reproducible Environment = Less …

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Visual Programming (S04 E01) 2:04:50

2y ago2:04:50

2:04:50

'Visual Programming' refers a style of programming that allows the user to specify a programs in a two-(or more)-dimensional fashion. Visual programming environments represent the data, control flow, or program state in a graphical way, allowing them to be directly manipulated. It has been a hot area of research from the very beginning of personal …

1
Lightning Network: Payments so small, it's a stream (S03 E10) 1:31:57

2y ago1:31:57

1:31:57

Lightning Network is a network of payment forwarders layered on top of Bitcoin to enable small, fast micropayments with low fees. Links/Resources: - https://lightning.network/ - https://www.swanbitcoin.com/a-look-at-the-lightning-network/ - [https://web.archive.org/web/20150301190111/http://lightning.network/lightning-network.pdf](https://web.archi…

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Hypercore: Lego Blocks for P2P Apps (S03E09) 1:14:20

2y ago1:14:20

1:14:20

Hypercore is a set of building blocks to build distributed peer-to-peer applications. It provides a variety of data structures, as well as a discovery mechanism to share data between peers. It is a suite of tools that are the Lego blocks to build peer-to-peer apps. Chapters: [00:00:00] Intros [00:02:16] What is Hypercore? [00:12:58] HyperDrive: A P…

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Datomic: Immutable database for new web architecture S03E08 1:02:05

2y ago1:02:05

1:02:05

Datomic is an immutable database that borrows ideas from functional programming. We discuss how an immutable database changes the architectural possibilities of web apps. Links/Resources: - [Datomic with Rich Hickey](https://www.youtube.com/watch?v=9TYfcyvSpEQ) - [Database as Values with Rich Hickey](https://www.youtube.com/watch?v=V6DKjEbdYos) - […

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Urbit: The Thousand Year Operating System (S03 E07) 1:47:07

2y ago1:47:07

1:47:07

Urbit is an operating system for a global networked computer with a global filesystem. It has its own virtual machine, programming language, OS kernel, and identity layer. It dubs itself as “A clean-slate OS and network for the 21st century.” Links/Resources: - https://media.urbit.org/whitepaper.pdf - https://developers.urbit.org/overview - https:/…

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Hyperfiddle: Compiler Managed Network Connections (S03 E06) 1:24:07

2y ago1:24:07

1:24:07

Hyperfiddle is an app builder in Clojure/Clojurescript that uses a compiler to manage the network connections in the app for you. We discuss what makes code easy vs simple, arches for software, home-cooked apps, and the implications of a compiler for everything. Links/Resources: - [https://www.hyperfiddle.net/](https://www.hyperfiddle.net/) - [http…

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Generative AI Models (S03 E05) 1:16:56

2y ago1:16:56

1:16:56

Generative AI models are quickly reaching the point where their work is indistinguishable from that of humans. This include 3D models, voice, and other media types that were not previously possible to create without significant expertise Resources [Google's New AI: Flying Through Virtual Worlds! 🕊️](https://www.youtube.com/watch?v=N-Pf9lCFi4E) [Ope…

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Zig: System programming without the warts (S03 E04) 59:50

2y ago59:50

59:50

Zig is a system programming language without the ugliness of C. We discuss its compile time features, its strive towards simplicity, and the potential for resource-efficient software. Links/Resources: • https://ziglang.org/learn/overview/ • https://www.youtube.com/watch?v=Gv2I7qTux7g • https://www.youtube.com/watch?v=Z4oYSByyRak • https://www.scatt…

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Multi-modal and Multi-task Models (S03 E04) 1:13:33

2y ago1:13:33

1:13:33

Multimodal and multitask models are machine learning models that can generalize. Multimodal models can generalize to understand different types of input, for example images and text. Multitask models can generalize their knowledge by applying what they’ve learned about one task to solve another task. Links/Resources: • MUM: https://blog.google/prod…

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Plan 9: The OS Where Everything is a File (S03 E02) 58:23

2y ago58:23

58:23

Plan 9 is distributed operating system and it is designed to make a network of disparate computers function as a single system no matter where they are. Links/Resources: https://9p.io/wiki/plan9/papers/ Chapters: 0:00 Intros 2:49 What is Plan 9? 6:15 Unique Features 9:23 Everything is a File 16:53 Assembling a Distributed Computer 21:42 Powerful Ab…

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Matrix: Let a Thousand Chat Clients Bloom (with Eric Migicovsky) S03 E01 1:07:20

2y ago1:07:20

1:07:20

Matrix is a decentralized chat protocol that is end-to-end encrypted. It lets users communicate with each other using different clients and even run their own independent chat servers. Links/Resources: - https://matrix.org/docs/guides/introduction - https://salibra.com/p/the-death-of-jabber-8ea395e82f5b- http://jabbermania.blogspot.com/2013/06/how-…

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Semantic Web (The Technium Podcast S02 E10) 1:13:09

2+ y ago1:13:09

1:13:09

The semantic web was an effort to mark up webpages with facts about their content. The dream was to enable computers, to understand the world by reading these webpages. We discuss why the effort failed, how it relates to symbolic AI/knowledge graphs, and how the vision could still be realized today. Links/Resources: Introducing the Knowledge Graph …

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TLA+ and Formal Methods (The Technium Podcast S02 E09) 1:11:19

2+ y ago1:11:19

1:11:19

TLA+ is a language for formally modeling and verifying the correctness of programs, especially concurrent and distributed ones. We discuss how it could be used to improve the practice of software engineering and what it would take for formal methods to gain more popularity. Links/Resources: TLA+ Homepage https://lamport.azurewebsites.net/tla/tla.ht…

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Transformers: One Model to Rule them All (The Technium Podcast S02 E08) 1:17:25

2+ y ago1:17:25

1:17:25

Transformers are a building block of Machine Learning systems that have seen great success recently at subsuming all other techniques. We discuss at a high level, its attention mechanism and its multimodal properties, and the types of applications this can be put to use now and in the future. Links/Resources: Introductions to transformers https://w…

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CORBA: Failed Distributed Architecture (The Technium Podcast S02 E07) 1:01:48

2+ y ago1:01:48

1:01:48

CORBA is an acronym that stands for common object request, broker architecture. It provides interoperability among distributed objects regardless of whether they're remote or local, regardless of whether they're written in different languages or in different locations of the network. We discuss its influence on distributed systems, and where we are…

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