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"Got Guts" The Micro Version: Electromechanical Coupling of the In-Vivo Pylorus

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Join coauthors Sam Simmonds, Ashton Matthee, and Timothy R. Angeli-Gordon as they delve into their recently published research, "Electromechanical Coupling and Anatomy of the In Vivo Gastroduodenal Junction." In this episode, they explore cutting-edge techniques like electrical mapping, impedance planimetry, and histological analysis to investigate the complex dynamics of the gastroduodenal junction. Discover how contractions in the terminal antrum and pyloric sphincter correlate with gastric slow waves, while the duodenum experiences bursts of spike activity that trigger oscillating contractions. The team discusses their intriguing hypothesis regarding the relative scarcity of myenteric interstitial cells of Cajal in the pylorus, which may hinder coupling between antral and duodenal slow waves.

Electromechanical coupling and anatomy of the in vivo gastroduodenal junction Sam Simmonds, Ashton Matthee, Jarrah M. Dowrick, Andrew J. Taberner, Peng Du, and Timothy R. Angeli-Gordon

American Journal of Physiology-Gastrointestinal and Liver Physiology 2024 327:1, G93-G104

  continue reading

41 episoade

Artwork
iconDistribuie
 
Manage episode 448032436 series 3332773
Content provided by ajpgi. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by ajpgi or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ro.player.fm/legal.

Join coauthors Sam Simmonds, Ashton Matthee, and Timothy R. Angeli-Gordon as they delve into their recently published research, "Electromechanical Coupling and Anatomy of the In Vivo Gastroduodenal Junction." In this episode, they explore cutting-edge techniques like electrical mapping, impedance planimetry, and histological analysis to investigate the complex dynamics of the gastroduodenal junction. Discover how contractions in the terminal antrum and pyloric sphincter correlate with gastric slow waves, while the duodenum experiences bursts of spike activity that trigger oscillating contractions. The team discusses their intriguing hypothesis regarding the relative scarcity of myenteric interstitial cells of Cajal in the pylorus, which may hinder coupling between antral and duodenal slow waves.

Electromechanical coupling and anatomy of the in vivo gastroduodenal junction Sam Simmonds, Ashton Matthee, Jarrah M. Dowrick, Andrew J. Taberner, Peng Du, and Timothy R. Angeli-Gordon

American Journal of Physiology-Gastrointestinal and Liver Physiology 2024 327:1, G93-G104

  continue reading

41 episoade

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