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023 - Depleted - How we are Beginning to Visulize the Tumor Microenvinroment

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Content provided by Keenan. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Keenan or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ro.player.fm/legal.

Welcome back! It's been a while. I'm excited to get going again with an episode on the emerging science of "ecotyping" the cells around tumors - the microenvironment. Ecology and Evolution of lymphoma tumors is only half the story. We needed to know more about the state of cells around the tumor. How do they affect the surrounding immune cells? Do they support the tumor? We examine the worst possible scenario: when very little remains except for tumor and support cells. What are the consequences for immune-specific therapies like CAR-T cells? Hopefully this episode provides a good intro to our new tools to measure the TME and how it can further advance precision cancer medicine. I hope that you enjoy!

Steen: https://pubmed.ncbi.nlm.nih.gov/34597589/

Katlov: https://pubmed.ncbi.nlm.nih.gov/33541860/

  continue reading

24 episoade

Artwork
iconDistribuie
 
Manage episode 356540446 series 2636038
Content provided by Keenan. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Keenan or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ro.player.fm/legal.

Welcome back! It's been a while. I'm excited to get going again with an episode on the emerging science of "ecotyping" the cells around tumors - the microenvironment. Ecology and Evolution of lymphoma tumors is only half the story. We needed to know more about the state of cells around the tumor. How do they affect the surrounding immune cells? Do they support the tumor? We examine the worst possible scenario: when very little remains except for tumor and support cells. What are the consequences for immune-specific therapies like CAR-T cells? Hopefully this episode provides a good intro to our new tools to measure the TME and how it can further advance precision cancer medicine. I hope that you enjoy!

Steen: https://pubmed.ncbi.nlm.nih.gov/34597589/

Katlov: https://pubmed.ncbi.nlm.nih.gov/33541860/

  continue reading

24 episoade

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