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🧬Cyriac Roeding - Part 3 | Founding Shopkick During the 2008 Financial Crisis | Transforming Retail with Mobile Tech | Exploring AI’s Use in Clinical Trials & Reshaping Drug Development
Manage episode 459567617 series 3461709
Content provided by Jon Chee. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Jon Chee or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ro.player.fm/legal.
Part 3 of 4: My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide.
Cyriac is a serial entrepreneur and investor who has created ventures at the intersection of physical and digital worlds. He has invested in startups like OpenAI and served as CEO of Shopkick, which was acquired for $250 million. His current focus, Earli, has raised nearly $60 million from top investors. Cyriac's journey from launching his first startup at 15 to being named a World Economic Forum Tech Pioneer showcases his valuable insights into building successful startups.
In this episode, you’ll hear about:
- Launching Shopkick during the 2008 financial crisis and securing funding against the odds
- Partnering with Best Buy, Macy’s, and Target to pioneer in-store rewards using ultrasound technology
- Overcoming GPS limitations with innovative hardware solutions
- Switching from retail tech to life sciences, with a focus on AI and engineering
- Cyriac’s vision for digital clinical trials to accelerate drug development
If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening!
Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994
Find Our Guest, Cyriac Roeding, at these links:
Find Our Host, Jon Chee, at these links:
Excedr Socials & Website
LinkedIn: https://www.linkedin.com/company/excedr/
Youtube: https://www.youtube.com/@excedr
Instagram: https://www.instagram.com/excedr_inc
Twitter: https://twitter.com/ExcedrInc
Facebook: https://www.facebook.com/excedr
TikTok: https://www.tiktok.com/@excedr
Podcast Website: https://www.thebiotechstartupspodcast.com/
Enriched Notes:
Topics Mentioned:
Earli: https://www.earli.com/
Kleiner Perkins: https://en.wikipedia.org/wiki/Kleiner_Perkins
Shopkick: https://en.wikipedia.org/wiki/Shopkick
AI in Drug Development & Clinical Trials: https://www.earli.com/post/how-ai-is-powering-earlis-mission
Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-support
People Mentioned:
John Doerr: https://www.linkedin.com/in/john-doerr-03248211/
Steve Jobs: https://en.wikipedia.org/wiki/Steve_Jobs
Reid Hoffman: https://www.linkedin.com/in/reidhoffman/
Aaron Emigh: https://www.linkedin.com/in/aaronemigh/
Alexis Rask: https://www.linkedin.com/in/aleinoff/
Timestamps:
00:00 Intro
01:58 Joining Kleiner Perkins as an entrepreneur-in-residence
05:43 Developing the idea for Shopkick
08:20 Securing Best Buy as a partner and navigating retailer challenges
11:11 Using ultrasound technology to solve GPS limitations for in-store tracking
13:25 Partnering with major brands and scaling Shopkick to profitability
16:25 Transitioning to life sciences and shifting focus to biology and AI
20:18 Exploring the potential of digital clinical trials
24:05 The intersection of biology, engineering, and software as the next frontier
27:57 Cyriac’s vision for the future of drug development
31:30 Outro
The Biotech Startups Podcast is handcrafted by our friends over at: fame.so
114 episoade
Manage episode 459567617 series 3461709
Content provided by Jon Chee. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Jon Chee or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ro.player.fm/legal.
Part 3 of 4: My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide.
Cyriac is a serial entrepreneur and investor who has created ventures at the intersection of physical and digital worlds. He has invested in startups like OpenAI and served as CEO of Shopkick, which was acquired for $250 million. His current focus, Earli, has raised nearly $60 million from top investors. Cyriac's journey from launching his first startup at 15 to being named a World Economic Forum Tech Pioneer showcases his valuable insights into building successful startups.
In this episode, you’ll hear about:
- Launching Shopkick during the 2008 financial crisis and securing funding against the odds
- Partnering with Best Buy, Macy’s, and Target to pioneer in-store rewards using ultrasound technology
- Overcoming GPS limitations with innovative hardware solutions
- Switching from retail tech to life sciences, with a focus on AI and engineering
- Cyriac’s vision for digital clinical trials to accelerate drug development
If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening!
Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994
Find Our Guest, Cyriac Roeding, at these links:
Find Our Host, Jon Chee, at these links:
Excedr Socials & Website
LinkedIn: https://www.linkedin.com/company/excedr/
Youtube: https://www.youtube.com/@excedr
Instagram: https://www.instagram.com/excedr_inc
Twitter: https://twitter.com/ExcedrInc
Facebook: https://www.facebook.com/excedr
TikTok: https://www.tiktok.com/@excedr
Podcast Website: https://www.thebiotechstartupspodcast.com/
Enriched Notes:
Topics Mentioned:
Earli: https://www.earli.com/
Kleiner Perkins: https://en.wikipedia.org/wiki/Kleiner_Perkins
Shopkick: https://en.wikipedia.org/wiki/Shopkick
AI in Drug Development & Clinical Trials: https://www.earli.com/post/how-ai-is-powering-earlis-mission
Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-support
People Mentioned:
John Doerr: https://www.linkedin.com/in/john-doerr-03248211/
Steve Jobs: https://en.wikipedia.org/wiki/Steve_Jobs
Reid Hoffman: https://www.linkedin.com/in/reidhoffman/
Aaron Emigh: https://www.linkedin.com/in/aaronemigh/
Alexis Rask: https://www.linkedin.com/in/aleinoff/
Timestamps:
00:00 Intro
01:58 Joining Kleiner Perkins as an entrepreneur-in-residence
05:43 Developing the idea for Shopkick
08:20 Securing Best Buy as a partner and navigating retailer challenges
11:11 Using ultrasound technology to solve GPS limitations for in-store tracking
13:25 Partnering with major brands and scaling Shopkick to profitability
16:25 Transitioning to life sciences and shifting focus to biology and AI
20:18 Exploring the potential of digital clinical trials
24:05 The intersection of biology, engineering, and software as the next frontier
27:57 Cyriac’s vision for the future of drug development
31:30 Outro
The Biotech Startups Podcast is handcrafted by our friends over at: fame.so
114 episoade
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The Biotech Startups Podcast
1 🧬 Rafael Rosengarten - Part 4 | Lessons in Scaling a Biotech Startup | Using AI to Transform Cancer Diagnostics | The Genialis Supermodel & krasID 40:45
40:45
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40:45🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 4 of 4 : My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI. Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics. In this episode, you'll hear about: Scaling Genialis during COVID-19 and refining the company’s mission The importance of company culture and building a motivated, cohesive team Developing krasID and the Genialis supermodel to advance cancer diagnostics Raising Series A funding amid biotech market challenges The role of leadership and innovation in driving biotech success and shaping the future of precision oncology. If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Rafael Rosengarten, at these links: https://www.linkedin.com/in/rrosengarten/ https://www.genialis.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Genialis: https://www.genialis.com/ Taiwania Capital: https://www.taiwaniacapital.com/ Debiopharm Innovation Fund: https://www.debiopharm.com/innovation-fund/ Genialis krasID: https://www.genialis.com/krasid/ Genialis Supermodel: https://www.genialis.com/supermodel/ How to Bootstrap a Biotech: https://www.excedr.com/resources/how-to-bootstrap-biotech-startup Biotech Funding Options: https://www.excedr.com/resources/biotech-startup-funding-options Top VCs in Biotech: https://www.excedr.com/blog/top-vc-firms-for-biotech AI in Cancer Diagnostics: https://www.frontiersin.org/articles/10.3389/fonc.2020.588221/full Predictive Biomarkers in Oncology: https://oncologypro.esmo.org/education-library/esmo-books/esmo-handbooks/translational-research/predictive-biomarkers How Biotech Partnerships Support Research: https://www.excedr.com/blog/how-biotech-partnerships-support-research People Mentioned: Cheng Wu (Founding Partner, Taiwania Capital): https://www.linkedin.com/in/cheng-wu-4614a8a/ Tiasha Stanković (COO, Head of People at Genialis): https://www.linkedin.com/in/tjasakk/?originalSubdomain=si Luka Ausec (Chief Discovery Officer at Genialis): https://www.linkedin.com/in/luka-ausec-378009150/ Miha Štajdohar (Co-founder, CTO at Genialis): https://www.linkedin.com/in/mstajdohar/ Marinka Zitnik (AI Researcher, Associate Professor of Bioinformatics): https://dbmi.hms.harvard.edu/people/marinka-zitnik Timestamps: 00:00 Intro 02:04 Scaling Genialis during COVID-19 and adapting as CEO 04:27 How pivotal clients influence a startup’s growth path 07:15 Addressing critical mistakes in clinical data pipelines 09:43 Redefining Genialis’ mission and fostering strong culture 12:19 Adapting to remote work while reinforcing team values 14:57 Raising Series A funding amid challenging market conditions 20:50 The importance of team culture and resilience 25:37 The Genialis supermodel and its impact on oncology AI 29:12 Two-year vision for Genialis and its three pillars 32:59 Closing questions and advice for entrepreneurs 38:59 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬 Rafael Rosengarten - Part 3 | Leveraging AI in Precision Medicine | How Predictive Biomarkers Transform Oncology | Lessons from Scaling a Startup 32:09
32:09
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32:09🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 3 of 4 : My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI. Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics. In this episode, you'll hear about: Rafael’s move to Baylor College of Medicine and Houston’s vibrant medical community Innovations in molecular cloning and synthetic biology tools at Baylor Bridging biology and AI through collaborations with University of Ljubljana researchers Founding Genialis and shifting its focus to predictive biomarker development Lessons from biotech pivots that shaped Genialis as a leader in precision oncology If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Rafael Rosengarten, at these links: https://www.linkedin.com/in/rrosengarten/ https://www.genialis.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Baylor College of Medicine: https://www.bcm.edu/ University of Ljubljana: https://www.uni-lj.si/en/university Genialis: https://www.genialis.com/ Lab Equipment List, Synthetic Biology Research: https://www.excedr.com/blog/lab-equipment-list-for-synthetic-biology-research How to Bootstrap Your Biotech Startup & Scale: https://www.excedr.com/resources/how-to-bootstrap-biotech-startup When & How to Pivot a Biotech Startup: https://www.excedr.com/blog/when-how-to-pivot-a-biotech-startup Biotech Startup Support Resources: https://www.excedr.com/resources-category/biotech-startup-support The Role of Machine Learning in Biotech: https://www.linkedin.com/pulse/machine-learning-biotech-fundamentals-divya-ramamoorthy-blhte/ Predictive Biomarkers in Oncology: https://oncologypro.esmo.org/education-library/esmo-books/esmo-handbooks/translational-research/predictive-biomarkers AI and Omics Analysis in Cancer Research: https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.588221/full Collaborative Biotech Partnerships: https://www.excedr.com/blog/how-biotech-partnerships-support-research People Mentioned: Gad Shaulsky: https://www.bcm.edu/people-search/gad-shaulsky-30425 Adam Kuspa: https://www.linkedin.com/in/adam-kuspa-23bab836/ Blaž Zupan: https://www.bcm.edu/people-search/blaz-zupan-33768 Marinka Zitnik: https://www.linkedin.com/in/marinkaz/ Miha Štajdohar: https://www.linkedin.com/in/mstajdohar/?originalSubdomain=si Laura Benjamin: https://www.linkedin.com/in/laura-e-benjamin-04299b34/ Timestamps: 00:00 Intro 02:11 Rafael’s move to Houston and postdoc at Baylor College of Medicine 04:09 Collaborating with mentors and early breakthroughs in molecular cloning 07:01 Joining the Gulf Coast Consortium and blending bench science with computational tools 09:44 Transformative partnership with AI pioneers from the University of Ljubljana 13:30 How early machine learning tools shaped Rafael’s career and perspective 17:04 Founding Genialis and the early challenges of pivoting its focus 19:59 Learning from failures and how they shaped Genialis’ mission 23:21 The role of predictive biomarkers in oncology and their real-world impact 27:59 Lessons learned from biotech pivots and navigating the startup world 31:16 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬 Rafael Rosengarten - Part 2 | From Marine Biology to Synthetic Biology | Building Biofuel Tools at JBEI | When Academic Labs Embrace Entrepreneurship 34:40
34:40
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34:40🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 2 of 4 : My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI. Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics. In this episode, you'll hear about: Rafael's graduate studies at Yale, where mentors fostered his independent research approach His diverse marine biology and genomics projects, preparing him for synthetic biology Rafael's transition to the Joint BioEnergy Institute (JBEI) for synthetic biology and biofuels research The collaborative environment at JBEI, including access to cutting-edge technology and bioinformatics tool development Rafael's insights on choosing the right lab environment and the growing acceptance of entrepreneurship in academia If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Rafael Rosengarten, at these links: https://www.linkedin.com/in/rrosengarten/ https://www.genialis.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Yale https://www.yale.edu/ Joint BioEnergy Institute (JBEI) https://www.jbei.org/ Next-Generation Sequencing https://www.excedr.com/blog/next-generation-sequencing-101 How to Spin Out of Academia & Into a Startup https://www.excedr.com/resources/how-to-spin-out-of-academia-and-into-a-startup What Should Investors & Founders Expect From Each Other https://www.excedr.com/resources/investor-founder-expectations How to Fund an R&D Startup https://www.excedr.com/resources/rd-startup-funding-first-steps People Mentioned: Stephen Dellaporta https://www.linkedin.com/in/stephen-dellaporta-442aa611/ Leo Buss https://eeb.yale.edu/people/faculty/leo-buss Barbara McClintock https://en.wikipedia.org/wiki/Barbara_McClintock Christopher Mason https://www.linkedin.com/in/christopher-mason-4972a119/ Jonathan Rothberg https://www.linkedin.com/in/jonathanrothberg/ Jay Keasling https://www.linkedin.com/in/jay-keasling-6783754/ Nathan Hillson https://www.linkedin.com/in/nathan-hillson-73702915/ Timestamps: 00:00 - Intro 02:56 - Rafael's experience with his graduate advisors and diverse research projects 07:45 - Comparison of grad school experience to company building and board members 08:59 - Discussion about Jonathan Rothberg and sequencing developments at Yale 10:06 - Rafael's transition from Yale to the Joint BioEnergy Institute (JBEI) 12:46 - The importance of showing up and making connections in person 16:39 - The value of face-to-face interactions in business and collaboration 20:19 - Challenges in the biotech market and the need for in-person networking 23:11 - Rafael's work at JBEI in synthetic biology and tool development 28:22 - Key takeaways from Rafael's experience at JBEI 30:25 - The importance of entrepreneurship in academia and industry 33:55 - Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬 Rafael Rosengarten - Part 1 | From Salt Marsh to Biotech CEO | Snorkeling into Science | Choosing Marine Biology Over Cooking on a Mediterranean Yacht 30:30
30:30
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30:30Part 1 of 4 : My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI. Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics. In this episode, you'll hear about: Rafael's upbringing in rural South Carolina, influenced by his parents' intellectual hippie activist background and nature How his French cell biologist uncle sparked his love for science through snorkeling Rafael's journey at Dartmouth, initially pursuing chemistry but ultimately finding his passion in evolutionary biology and ecology His post-college experiences alternating between scientific research and culinary pursuits The pivotal decision to attend a marine biology program at Friday Harbor instead of accepting an offer to cook on a private yacht If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Rafael Rosengarten, at these links: https://www.linkedin.com/in/rrosengarten/ https://www.genialis.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Dartmouth https://home.dartmouth.edu/ Bay Wolf https://www.berkeleyside.org/2015/07/01/oaklands-bay-wolf-restaurant-closing-after-40-years Yale https://www.yale.edu/ Chez Panisse https://www.chezpanisse.com/1/ Friday Harbor Laboratories https://fhl.uw.edu/ People Mentioned: Jay Keasling https://www.linkedin.com/in/jay-keasling-6783754/ Mark McPeak https://biology.dartmouth.edu/people/mark-alan-mcpeek David Peart https://www.linkedin.com/in/david-peart-251787302/ Carol Folt https://biology.dartmouth.edu/people/carol-l-folt Leo Buss https://eeb.yale.edu/people/faculty/leo-buss Alice Waters https://en.wikipedia.org/wiki/Alice_Waters Fanny Singer (Waters) https://thefoldmag.com/arts-culture/a-conversation-with-fanny-singer-about-her-mother-daughter-memoir-always-home Jeremiah Tower https://www.linkedin.com/in/jeremiah-tower/ Dan Barber https://en.wikipedia.org/wiki/Dan_Barber Thomas Keller https://en.wikipedia.org/wiki/Thomas_Keller Timestamps: 00:49 Intro 02:48 Rafael's upbringing in rural South Carolina and early influences 05:50 Discussing the impact of Rafael's upbringing on his business philosophy 07:44 Rafael's decision to attend Dartmouth College 10:27 Family influence on Rafael's academic pursuits 12:04 Rafael's experiences at Dartmouth and choosing his major 14:30 Summer internship at Bay Wolf restaurant in Oakland 16:55 Influential professors and classmates at Dartmouth 18:22 Post-graduation experiences and working at Yale 23:20 Comparing cooking experiences on the West Coast and East Coast 26:38 Entering Yale's biomedical program and the Friday Harbor experience 29:48 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬 Cyriac Roeding - Part 4 | Revolutionizing Cancer Detection & Therapy | Harnessing Synthetic Biology to Reshape Diagnostics | Solving Biotech’s Toughest Problems 37:38
37:38
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37:38Part 4 of 4 : My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide. Cyriac is a serial entrepreneur and investor who has created ventures at the intersection of physical and digital worlds. He has invested in startups like OpenAI and served as CEO of Shopkick, which was acquired for $250 million. His current focus, Earli, has raised nearly $60 million from top investors. Cyriac's journey from launching his first startup at 15 to being named a World Economic Forum Tech Pioneer showcases his valuable insights into building successful startups. In this episode, you’ll hear about: How a Thanksgiving article about Dr. Sam Gambhir inspired the founding of Earli Earli’s groundbreaking approach to revolutionizing cancer detection using synthetic biology The challenges of translating scientific discoveries into real-world clinical applications Overcoming obstacles and achieving breakthroughs in diagnostics and therapeutics Cyriac’s unwavering commitment to transforming cancer into a manageable condition If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Cyriac Roeding, at these links: https://www.linkedin.com/in/cyriacroeding/ https://www.earli.com/ https://www.joinrewind.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Earli: https://www.earli.com/ Stanford University: https://www.stanford.edu/ Andreessen Horowitz: https://a16z.com/ Marc Benioff: https://www.linkedin.com/in/marcbenioff/ Khosla Ventures: https://www.khoslaventures.com/ Lab Equipment List, Synthetic Biology Research: https://www.excedr.com/blog/lab-equipment-list-for-synthetic-biology-research How to Bootstrap Your Biotech Startup & Scale: https://www.excedr.com/resources/how-to-bootstrap-biotech-startup When & How to Pivot a Biotech Startup: https://www.excedr.com/blog/when-how-to-pivot-a-biotech-startup How to Craft a Pitch Deck for Biotech Investors: https://www.excedr.com/resources/how-to-craft-a-pitch-deck-for-biotech-investors Top VC Firms for Biotech in 2024: https://www.excedr.com/blog/top-vc-firms-for-biotech Biotech Startup Support Resources: https://www.excedr.com/resources-category/biotech-startup-support People Mentioned: Dr. Sam Gambhir: https://en.wikipedia.org/wiki/Sanjiv_Sam_Gambhir David Suhy: https://www.linkedin.com/in/davidsuhy/ Jorge Conde: https://www.linkedin.com/in/jorge-conde-4099225/ Jim Allison: https://faculty.mdanderson.org/profiles/james_allison.html Pam Sharma: https://faculty.mdanderson.org/profiles/padmanee_sharma.html Phil Greenberg: https://www.fredhutch.org/en/faculty-lab-directory/greenberg-philip.html Timestamps: 00:00 Intro 02:08 How a Thanksgiving article about Dr. Sam Gambhir inspired Earli’s founding 05:43 Meeting Dr. Gambhir and learning biology as a non-scientist entrepreneur 09:02 Discovering the “one idea” that led to Earli’s revolutionary synthetic biology approach 12:54 Earli’s mission to transform cancer detection and diagnostics 17:30 Overcoming major challenges and achieving breakthroughs in diagnostics accuracy 21:54 The emotional and scientific legacy of Dr. Gambhir and its impact on Earli’s vision 26:28 Earli’s innovative approach to bridging diagnostics and therapeutics 30:05 The business potential of Earli’s platform for cancer and other diseases 33:04 Cyriac’s advice on taking the road less traveled as an entrepreneur 35:41 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬Cyriac Roeding - Part 3 | Founding Shopkick During the 2008 Financial Crisis | Transforming Retail with Mobile Tech | Exploring AI’s Use in Clinical Trials & Reshaping Drug Development 32:18
32:18
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32:18Part 3 of 4 : My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide. Cyriac is a serial entrepreneur and investor who has created ventures at the intersection of physical and digital worlds. He has invested in startups like OpenAI and served as CEO of Shopkick, which was acquired for $250 million. His current focus, Earli, has raised nearly $60 million from top investors. Cyriac's journey from launching his first startup at 15 to being named a World Economic Forum Tech Pioneer showcases his valuable insights into building successful startups. In this episode, you’ll hear about: Launching Shopkick during the 2008 financial crisis and securing funding against the odds Partnering with Best Buy, Macy’s, and Target to pioneer in-store rewards using ultrasound technology Overcoming GPS limitations with innovative hardware solutions Switching from retail tech to life sciences, with a focus on AI and engineering Cyriac’s vision for digital clinical trials to accelerate drug development If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Cyriac Roeding, at these links: https://www.linkedin.com/in/cyriacroeding/ https://www.earli.com/ https://www.joinrewind.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Earli: https://www.earli.com/ Kleiner Perkins: https://en.wikipedia.org/wiki/Kleiner_Perkins Shopkick: https://en.wikipedia.org/wiki/Shopkick AI in Drug Development & Clinical Trials: https://www.earli.com/post/how-ai-is-powering-earlis-mission Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-support People Mentioned: John Doerr: https://www.linkedin.com/in/john-doerr-03248211/ Steve Jobs: https://en.wikipedia.org/wiki/Steve_Jobs Reid Hoffman: https://www.linkedin.com/in/reidhoffman/ Aaron Emigh: https://www.linkedin.com/in/aaronemigh/ Alexis Rask: https://www.linkedin.com/in/aleinoff/ Timestamps: 00:00 Intro 01:58 Joining Kleiner Perkins as an entrepreneur-in-residence 05:43 Developing the idea for Shopkick 08:20 Securing Best Buy as a partner and navigating retailer challenges 11:11 Using ultrasound technology to solve GPS limitations for in-store tracking 13:25 Partnering with major brands and scaling Shopkick to profitability 16:25 Transitioning to life sciences and shifting focus to biology and AI 20:18 Exploring the potential of digital clinical trials 24:05 The intersection of biology, engineering, and software as the next frontier 27:57 Cyriac’s vision for the future of drug development 31:30 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬 Cyriac Roeding - Part 2 | From Digital Clocks to Global Mobile Marketing | Cracking Coca-Cola's 160 Million Bottle Code | Silicon Valley's Pine-Scented Entrepreneurship | Leapfrogging Technology… 30:44
30:44
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30:44🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 2 of 4 : My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide. Cyriac is a serial entrepreneur and investor who has created ventures at the intersection of physical and digital worlds. He has invested in startups like OpenAI and served as CEO of Shopkick, which was acquired for $250 million. His current focus, Earli, has raised nearly $60 million from top investors. Cyriac's journey from launching his first startup at 15 to being named a World Economic Forum Tech Pioneer showcases his valuable insights into building successful startups. In this episode, you’ll hear about: How Cyriac's early fascination with technology manifested through building a digital clock from scratch The transformative experience in Tokyo that served as a "reset button," exposing him to radical cultural differences His strategic career progression from Roland Berger to McKinsey The pivotal move from a failing mobile auction business to pioneering "mobile marketing" The challenging transition to CBS Mobile, where starting from zero employees allowed him to leapfrog competitors by implementing innovative features If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Links Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Cyriac Roeding, at these links: https://www.linkedin.com/in/cyriacroeding/ https://www.earli.com/ https://www.joinrewind.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Earli Inc https://www.earli.com/ Roland Berger https://en.wikipedia.org/wiki/Roland_Berger_(company) McKinsey https://en.wikipedia.org/wiki/McKinsey_%26_Company CBS https://en.wikipedia.org/wiki/CBS People Mentioned: Chris Burggraeve https://www.linkedin.com/in/chrisburggraeve/ David Katz https://www.linkedin.com/in/davidakatz1/ Nancy Tellem https://www.linkedin.com/in/nancy-tellem-5a3b8311/ Timestamps: 00:00 Introduction and recap of previous episode with Cyriac Roeding 02:06 Cyriac's experience moving to Japan and cultural observations 03:58 Early technology interests: building digital clocks and programming robots 07:44 Discussion on trial and error in business and innovation 09:21 First job experiences at Roland Berger consulting in Tokyo and Munich 12:14 Journey to McKinsey and writing "The Secrets of Software Success" 14:09 First visit to Silicon Valley and falling in love with the entrepreneurial spirit 16:20 Starting a mobile technology company during the dot-com era 20:26 Success with Coca-Cola mobile marketing campaign and company profitability 22:01 Moving to CBS and initial challenges in Los Angeles 25:06 Building CBS Mobile strategy and innovative mobile initiatives 27:06 World travels observing mobile phone usage across different cultures 29:52 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬 Cyriac Roeding - Part 1 | From Flea Market Entrepreneur to Silicon Valley CEO | Reinvention During an Exchange Year | Finding Perspective in Japanese Business Culture 37:18
37:18
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37:18🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 1 of 4 : My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide. Cyriac is a serial entrepreneur and investor who has created ventures at the intersection of physical and digital worlds. He has invested in startups like OpenAI and served as CEO of Shopkick, which was acquired for $250 million. His current focus, Earli, has raised nearly $60 million from top investors. Cyriac's journey from launching his first startup at 15 to being named a World Economic Forum Tech Pioneer showcases his valuable insights into building successful startups. In this episode, you’ll hear about: How Cyriac's entrepreneurial journey began at age 8 selling at flea markets, leading to selling his first computer program at 15 to a newspaper company His transformative exchange year in Texas at age 16 and how it allowed Cyriac to reset his identity How his graduation event transformed his school into a beach with Coca-Cola sponsorship and TV coverage How he created and hosted a late-night radio show, balancing academic demands with creative pursuits How his experience studying in Japan revealed valuable lessons about cultural perspectives If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Cyriac Roeding, at these links: https://www.linkedin.com/in/cyriacroeding/ https://www.earli.com/ https://www.joinrewind.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Earli Inc https://www.earli.com/ Karlsruhe Institute of Technology https://www.kit.edu/english/index.php People Mentioned: Marc Benioff https://www.linkedin.com/in/marcbenioff/ Timestamps: 00:00 Intro 03:06 Early life in Germany and first entrepreneurial experiences at local flea markets 05:03 First job experience at a newspaper company and selling software at age 15 08:59 Exchange student experience in Texas and transformation from German school life 10:52 Life with host families in Texas and personal growth 14:29 Return to Germany and fresh start at a new school 16:31 Early business ventures, teaching computer skills and running a company at 17 20:14 High school graduation and organizing a Coca-Cola sponsored beach event 21:37 University decisions and pursuing industrial engineering at Karlsruhe Institute of Technology 26:54 Journey to studying in Japan and securing a scholarship 30:44 Cultural lessons in Japan: experiencing different value systems and problem-solving approaches 36:30 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬 Kate Neville - Part 4 | Balancing IP Enforcement & Licensing | Leveraging Shelved Pharma Assets | Building Resilient IP Portfolios 31:48
31:48
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31:48🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 4 of 4 : In this episode, Jon Chee hosts Kate Neville, PhD, Partner at Marshall Gerstein—a law firm with over 60 years of expertise in delivering sophisticated intellectual property advice and legal services to leading businesses, research institutions, universities, and entrepreneurs worldwide. Kate is an accomplished attorney with a doctoral background in microbiology and immunology who specializes in global patent prosecution and strategic management. She has over a decade of experience, and works with a wide range of clients, from biotech startups to big pharma to non-profits. Kate has been recognized as a "World's Leading Patent Practitioner" by IAM magazine since 2013, an Illinois Super Lawyer since 2018, and is included in The Best Lawyers in America© for Patent Law. In this episode, you’ll hear about: Why securing a patent is only the first step in IP protection Weighing litigation versus licensing to safeguard your IP Leveraging technology transfer and academic collaborations for innovation Driving innovation through incremental advancements in your IP portfolio Kate’s journey from scientist to partner, with insightful advice for those navigating career transitions If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Kate Neville, at these links: https://www.linkedin.com/in/kate-neville-phd/ https://www.marshallip.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Marshall Gerstein: https://www.marshallip.com/ IP Enforcement Strategies: https://www.wipo.int/en/web/ip-enforcement/ IP Strategies for Biotechs: https://www.excedr.com/resources/intellectual-property-strategy-for-biotechs IP Rights to Understand: https://www.excedr.com/resources/intellectual-property-rights-for-biotechs Intellectual Property 101: https://www.excedr.com/resources/intellectual-property-guide Tech Transfer 101: https://www.excedr.com/blog/what-is-tech-transfer Patent Licensing 101: https://www.excedr.com/resources/how-patent-licensing-works Guide to Life Sciences Licensing: https://www.excedr.com/blog/life-sciences-licensing-agreements-guide Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-support Timestamps: 00:00 Intro 02:04 The challenges of enforcing IP protections 03:46 Balancing litigation and licensing as a business decision 07:13 Technology transfer breakdown and how to secure your next big idea 09:07 Exploring shelved pharma compounds as IP opportunities 11:29 Avoiding common IP pitfalls for biotech startups 14:10 The value of fresh perspectives in biotech entrepreneurship 16:35 Challenges of transitioning from the bench to law practice 20:52 Insights into life as a partner in an IP law firm 23:09 2-year vision at Marshall Gerstein 26:42 Closing questions and advice for biotech founders 29:47 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬Kate Neville - Part 3 | Fundamentals of IP Strategy for Biotechs | Safeguarding Discoveries & Technology | Aligning Science with Patents | Navigating Global Patent Considerations 29:53
29:53
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29:53🧬The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗Get your unique referral link here : refer.excedr.com/ZTHETY . Part 3 of 4 : In this episode, Jon Chee hosts Kate Neville, PhD, Partner at Marshall Gerstein—a law firm with over 60 years of expertise in delivering sophisticated intellectual property advice and legal services to leading businesses, research institutions, universities, and entrepreneurs worldwide. Kate is an accomplished attorney with a doctoral background in microbiology and immunology who specializes in global patent prosecution and strategic management. She has over a decade of experience, and works with a wide range of clients, from biotech startups to big pharma to non-profits. Kate has been recognized as a "World's Leading Patent Practitioner" by IAM magazine since 2013, an Illinois Super Lawyer since 2018, and is included in The Best Lawyers in America© for Patent Law. In this episode, you’ll hear about: Building a strong foundation for your IP and the importance of well-crafted provisional applications. Aligning scientific advancements with proactive patent strategies to maximize long-term value. The critical timing for startups to address IP concerns, from tech transfer to scaling operations. The nuances of international patenting and strategic decisions on global protections. Practical tips for founders on prioritizing IP investments to strengthen their company and attract investors. If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Kate Neville, at these links: https://www.linkedin.com/in/kate-neville-phd/ https://www.marshallip.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Marshall Gerstein: https://www.marshallip.com/ Intellectual Property 101: https://www.excedr.com/resources/intellectual-property-guide How to Protect Your IP in the Life Sciences: https://www.excedr.com/resources/how-to-protect-your-intellectual-property IP Strategy for Biotechs: https://www.excedr.com/resources/intellectual-property-strategy-for-biotechs Understanding IP Rights for Biotechs: https://www.excedr.com/resources/intellectual-property-rights-for-biotechs Patent Licensing 101: https://www.excedr.com/resources/how-patent-licensing-works Resources for Biotech Startups: https://www.excedr.com/resources/ Timestamps: 00:00 Intro 02:09 How to approach intellectual property (IP) as a biotech startup 05:06 When to start thinking about your IP portfolio and strategy 08:52 How much time does it take to protect your IP, and what are the phases? 11:26 Some best practices for global IP protections 14:07 Importance of patents to investors, and the timing behind raising capital 15:54 How does IP strategy differ from company to company? 17:37 Patent offices’ outlook on broad platform protections 22:18 Thought process behind picking which IP to hold or sell 25:01 Fundamental aspects of a solid IP strategy 29:08 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬Kate Neville - Part 2 | Navigating Law School as a Scientist | From Patent Agent to Lawyer | Thriving at the Intersection of Science & Law | Continuous Learning in Diverse Scientific Fields 20:50
20:50
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20:50🧬The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗Get your unique referral link here : refer.excedr.com/ZTHETY . Part 2 of 4 : Jon Chee hosts Kate Neville, Partner at Marshall Gerstein—a law firm with over 60 years of expertise in delivering sophisticated intellectual property advice and legal services to leading businesses, research institutions, universities, and entrepreneurs worldwide. Kate, an accomplished attorney with a doctoral background in microbiology and immunology, specializes in global patent prosecution and strategic management. With over a decade of experience, she works with biotech startups, big pharma, and non-profits. Kate has been recognized as a "World's Leading Patent Practitioner" by IAM magazine since 2013, an Illinois Super Lawyer since 2018, and is included in The Best Lawyers in America© for Patent Law. Join us this week to hear about: Kate's transition from patent agent to lawyer, highlighting challenges of pursuing a law degree while working full-time The culture shock scientists face in law school, adjusting to ambiguity and lack of definitive answers The extensive reading required in law school compared to scientific literature, requiring a different approach The collegial culture at Kate's law firm, fostering an environment where former scientists can thrive How patent law work provides exposure to diverse scientific fields, offering continuous learning opportunities Please enjoy Jon’s conversation with Kate Neville. Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Kate Neville, at these links: https://www.linkedin.com/in/kate-neville-phd/ https://www.marshallip.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Marshall, Gerstein & Borun https://www.marshallip.com/ Business Entities & Their Differences https://www.excedr.com/resources/what-are-the-differences-between-business-entities Intellectual Property 101: Types & Uses https://www.excedr.com/resources/intellectual-property-guide How to Protect Your Intellectual Property in the Life Sciences https://www.excedr.com/resources/how-to-protect-your-intellectual-property Timestamps: 00:00 Intro 02:24 Kate discusses taking the patent bar and transitioning from patent agent to pursuing law school 04:14 Experience of working full-time while attending law school at night 06:56 Challenges scientists face when transitioning to law school, particularly dealing with ambiguity 09:28 Discussion about the different types of reading required in law school versus scientific papers 12:20 Kate describes her law firm's culture and what made her stay throughout her career 16:02 Benefits of having broad scientific knowledge and crossdisciplinary experience 18:49 Working with scientist clients and keeping up with evolving technologies 20:05 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬 Kate Neville - Part 1 | From Youngest of Six to Patent Law Pioneer | When Chemistry Sets Spark Scientific Careers | Leading Through Autonomy | Serendipitous Path from Lab Bench to IP Law 28:01
28:01
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28:01The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 1 of 4 : Jon Chee hosts Kate Neville, Partner at Marshall Gerstein—a law firm with over 60 years of expertise in delivering sophisticated intellectual property advice and legal services to leading businesses, research institutions, universities, and entrepreneurs worldwide. Kate, an accomplished attorney with a doctoral background in microbiology and immunology, specializes in global patent prosecution and strategic management. With over a decade of experience, she works with biotech startups, big pharma, and non-profits. Kate has been recognized as a "World's Leading Patent Practitioner" by IAM magazine since 2013, an Illinois Super Lawyer since 2018, and is included in The Best Lawyers in America© for Patent Law. Join us this week to hear about: How growing up as youngest of six influenced Kate's leadership style of giving autonomy while providing guidance How early exposure to science through her father's engineering and a chemistry set ignited her scientific interests The research at Michigan's yeast lab and Northwestern's MS research that developed key multitasking abilities Kate’s unexpected shift from bench science to patent law through colleagues at Marshall Gerstein How career paths in science evolved from strictly academic to broader acceptance of industry and alternative paths Please enjoy Jon’s conversation with Kate Neville. Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Kate Neville, at these links: https://www.linkedin.com/in/kate-neville-phd/ https://www.marshallip.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Marshall, Gerstein & Borun https://www.marshallip.com/ Northwestern University https://www.northwestern.edu/ Business Entities & Their Differences https://www.excedr.com/resources/what-are-the-differences-between-business-entities Intellectual Property 101: Types & Uses https://www.excedr.com/resources/intellectual-property-guide How to Protect Your Intellectual Property in the Life Sciences https://www.excedr.com/resources/how-to-protect-your-intellectual-property People Mentioned: Sharon Sintich https://www.linkedin.com/in/sharon-sintich-2033462a/ Stephen Miller https://www.feinberg.northwestern.edu/faculty-profiles/az/profile.html?xid=14949 Timestamps: 00:00 Intro 03:26 Kate's background growing up as the youngest of six children 05:36 Kate's leadership style and approach to management 07:33 Early exposure to science and developing an interest in chemistry 09:27 Exploring different scientific fields in university 11:56 Considering career paths and deciding on graduate school 12:54 Undergraduate lab experiences and summer research program 15:29 Choosing Northwestern for PhD and focus on immunology 18:29 Challenges and triumphs during graduate studies 21:43 Serendipitous introduction to patent law as a career path 25:05 Changing perceptions of non-academic career paths in science 27:22 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬 Barry Ticho - Part 4 | Founding Verve Therapeutics Over Breakfast | Gene Editing for Cardiovascular Disease | Leadership Lessons From a First-Time Founder | Stoke’s Vision for RNA-Based Medicines 39:40
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39:40The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 4 of 4 : Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines. With an MD PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas. Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field. Join us this week to hear about: Founding Verve Therapeutics and pioneering gene editing for cardiovascular disease Tackling medicine adherence with one-and-done gene therapies Leadership lessons from starting and scaling biotech startups How patient stories inspire innovation in genetic medicine Stoke’s vision for genetic medicine and transformative treatments for diseases like Dravet syndrome Please enjoy Jon’s conversation with Barry Ticho. Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Barry Ticho, at these links: https://www.linkedin.com/in/barryticho/ https://www.stoketherapeutics.com/ https://www.vervetherapeutics.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Verve Therapeutics: https://www.vervetx.com/ Stoke Therapeutics: https://www.stoketherapeutics.com/ Google Ventures: https://www.gv.com/ Mass General Hospital: https://www.massgeneral.org/ Brigham and Women’s Hospital: https://www.brighamandwomens.org/ Biogen: https://www.biogen.com/ University of Pennsylvania: https://www.upenn.edu/ Gene Editing and Its Impact on Cardiovascular Disease: https://www.health.harvard.edu/heart-health/gene-therapy-for-cardiovascular-disease RNA-Based Medicines for Rare Disease Treatment: https://www.nature.com/articles/s41419-022-05075-2 Biotech Partnerships With Big Pharma: https://www.excedr.com/blog/how-biotech-partnerships-support-research Business Development in Biotech: https://www.excedr.com/resources/business-development-in-the-life-sciences Biotech Funding Options: https://www.excedr.com/resources/biotech-startup-funding-options Scaling Biotechs to Meet Key Milestones with Leasing: https://www.excedr.com/blog/how-leasing-helps-biotechs-scale-efficiently People Mentioned: Sekar Kathiresan: https://www.linkedin.com/in/sekar-sek-kathiresan-3501846/ Timestamps: 00:00 Intro 02:15 Founding Verve Therapeutics over breakfast 05:31 Gene editing for cardiovascular disease: The PCSK9 story 07:49 Barry’s experience as a first-time CEO 12:01 Joining Stoke Therapeutics and exploring RNA-based medicines 16:56 Building strong networks and the value of professional connections 22:09 Transitioning Stoke from private to public company 26:29 Hiring wisely and making difficult decisions quickly 30:09 Chief medical officer lessons: patient focus and team amplification 33:25 Stoke’s future: Dravet syndrome trials and pipeline expansion 35:12 Shouts and advice to younger self 37:23 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬 Barry Ticho - Part 3 | Lessons From Rigorous Drug Development | Industry vs. Academic Research Standards | A Patient-Centered Approach to Clinical Trials | How RNA is Shaping Modern Medicine 37:09
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37:09The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 3 of 4 : Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines. With an MD PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas. Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field. Join us this week to hear about: Barry’s switch from academia to industry, and the challenges of his role at Merck Navigating drug development and the rigorous standards of pharmaceutical research Leading patient-centered clinical development at Biogen to create impactful therapies Exploring the potential of RNA medicine at Pfizer and Moderna Working on Moderna’s lipid nanoparticle technology, the basis for the COVID-19 vaccine Please enjoy Jon’s conversation with Barry Ticho. Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Barry Ticho, at these links: https://www.linkedin.com/in/barryticho/ https://www.stoketherapeutics.com/ https://www.vervetherapeutics.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Topics Mentioned: Merck: https://www.merck.com/ Biogen: https://www.biogen.com/ Pfizer: https://www.pfizer.com/ Wave Biosciences: https://wavelifesciences.com/ Moderna: https://www.modernatx.com/en-US Verve Therapeutics: https://www.vervetx.com/ People Mentioned: Stéphane Bancel: https://www.linkedin.com/in/st%C3%A9phane-bancel-8185251 Timestamps: 00:00 Intro 02:06 Transitioning from academia to Merck 03:41 Rigorous drug development processes at Merck 06:00 Industry vs. academia: reproducibility and research quality in pharma 08:35 Patient-centered clinical trials at Biogen 09:45 Phases of clinical trials and ensuring patient access 14:06 Challenges in drug approval: biology, regulations, and precision medicine 18:24 Biogen’s focus on impactful therapies for severe diseases 23:14 Joining Pfizer for cardiovascular research and RNA exploration 27:04 Exploring RNA therapeutics at Pfizer and transitioning to Moderna 30:21 Driving lipid nanoparticle breakthroughs at Moderna 36:23 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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The Biotech Startups Podcast
1 🧬Barry Ticho - Part 2 | Zebrafish Hearts & Pediatric Cardiology | Balancing Lab Work & Clinical Practice | Navigating Academic Medicine's Challenges | The Draw of Biopharma & Translational Medicine 28:04
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28:04The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 2 of 4 : Jon Chee hosts Barry Ticho, Founder of Verve Therapeutics and Chief Medical Officer at Stoke Therapeutics, a biotech company addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines. With an MD-PhD from the University of Chicago and extensive experience across academia and industry, Barry brings over two decades of expertise in clinical development. His journey includes roles as Head of Development at Moderna, Head of External R&D Innovation at Pfizer, and VP of Clinical Development at Biogen, where he's been instrumental in advancing numerous therapeutic programs across multiple disease areas. Barry's unique perspective spanning academic medicine and biotechnology innovation makes his insights invaluable for aspiring leaders in the field. Join us this week to hear about: Pioneering research using transparent zebrafish embryos to study cardiac development Helping establish the myCHOICE program at University of Chicago Managing concurrent roles at Harvard Medical School and Mass General Gaining invaluable crisis management experience as a pediatric cardiologist leading emergency resuscitations Making the strategic career transition to biopharma to combine basic science with clinical work Please enjoy Jon’s conversation with Barry Ticho. Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Barry Ticho, at these links: https://www.linkedin.com/in/barryticho/ https://www.stoketherapeutics.com/ https://www.vervetherapeutics.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Stoke Therapeutics https://www.stoketherapeutics.com/ Verve Therapeutics https://www.vervetherapeutics.com/ University of Chicago https://www.uchicago.edu/en Harvard Medical School https://hms.harvard.edu/ Boston Children's Hospital https://www.childrenshospital.org/ Massachusetts General Hospital https://www.massgeneral.org/ Northwestern University https://www.northwestern.edu/ How to Spin Out of Academia: https://www.excedr.com/resources/how-to-spin-out-of-academia-and-into-a-startup Breaking into BD as a PhD Student https://www.excedr.com/blog/how-to-break-into-biotech-bd-as-a-phd-student Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-support Medical Imaging: Modalities & Types of Equipment https://www.excedr.com/blog/medical-imaging-and-radiology-overview People Mentioned: Mark Fishman https://www.linkedin.com/in/mark-fishman-1b1368182/ Timestamps: 00:00 Intro 02:16 Transitioning from grad school to Harvard and Boston Children's Hospital 04:19 The importance of rotations and exploring different career paths 06:48 Fascination with cardiac development: From four cells to a complex organ 08:24 Advice on continuous learning and career exploration 10:49 The shift in academia: From textbooks to startups 12:09 Zebrafish research: Transparent insights into cardiac development 14:44 The rewards and challenges of practicing pediatric cardiology 16:57 Learning from brilliant colleagues: "Steel sharpens steel" 18:18 Avoiding comparison: "Comparison is the thief of joy" 20:59 Gaining perspective on emergencies: From cardiac arrests to business crises 23:46 The catalyst for transitioning to industry: Combining science and clinical interests 26:27 The changing landscape of medicine and the appeal of biopharma 27:18 Outro The Biotech Startups Podcast is handcrafted by our friends over at: fame.so…
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