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Genome Editing: Fetal Origins of AML in Down Syndrome, With Drs. Adam Mead & Elvin Wagenblast

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Content provided by The Hematologist. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by The Hematologist or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ro.player.fm/legal.

In this podcast, Contributing Editor Dr. Adam Mead has a conversation with Dr. Elvin Wagenblast. They discuss Dr. Mead’s Diffusion article from the September/October 2021 issue of The Hematologist, titled, "Genome Editing: The Fetal Origins of Acute Myeloid Leukemia in Down Syndrome." They discuss a study that used CRISPR/Cas9 genome editing of hematopoietic stem and progenitor cells from human fetal liver to induce transient abnormal myelopoiesis– and myeloid leukemia associated with Down syndrome–related mutations. You can access his Diffusion article online at https://ashpublications.org/thehematologist/article/doi/10.1182/hem.V18.5.202159/476568/Genome-Editing-the-Fetal-Origins-of-Acute-Myeloid.
Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/

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143 episoade

Artwork
iconDistribuie
 
Manage episode 302587958 series 2981732
Content provided by The Hematologist. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by The Hematologist or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ro.player.fm/legal.

In this podcast, Contributing Editor Dr. Adam Mead has a conversation with Dr. Elvin Wagenblast. They discuss Dr. Mead’s Diffusion article from the September/October 2021 issue of The Hematologist, titled, "Genome Editing: The Fetal Origins of Acute Myeloid Leukemia in Down Syndrome." They discuss a study that used CRISPR/Cas9 genome editing of hematopoietic stem and progenitor cells from human fetal liver to induce transient abnormal myelopoiesis– and myeloid leukemia associated with Down syndrome–related mutations. You can access his Diffusion article online at https://ashpublications.org/thehematologist/article/doi/10.1182/hem.V18.5.202159/476568/Genome-Editing-the-Fetal-Origins-of-Acute-Myeloid.
Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/

  continue reading

143 episoade

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