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Talking Meds - A PrescQIPP podcast Episode 3
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Welcome to the latest episode of Talking Meds and the PrescQIPP podcast, engaging conversations about medicines-related dilemmas.
Today Jonathan Underhill, Medicines Clinical Adviser at PrescQIPP, talks to Dr Mark Horowitz about how to safely stop antidepressants and the importance of tapering dose reduction slowly to reduce the risk of withdrawal symptoms.
Dr Mark Horowitz is a training psychiatrist and Visiting Lecturer in London, and the lead author of the Maudsley Deprescribing Guidelines (see below). Mark co-authored the recent Royal College of Psychiatrists’ guidance on ‘Stopping Antidepressants’, and has been commissioned by Health Education England to prepare a teaching module on how to safely stop antidepressants for the NHS (coming soon!).
Mark has experienced the difficulty of coming off psychiatric medications first hand which has informed much of his work.
Useful sources referred to in this episode include:
Dose response curves/Law of Mass action illustrated here (see figure 1)
The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs
RPS members can get free access to the Maudsley Deprescribing Guidelines here:
https://www.vlebooks.com/Account/Logon/RPS
Maudsley Prescribing Guidelines
The Maudsley Prescribing Guidelines in Psychiatry eBook
Register for an NHS England OpenAthens account.
NICE guidelines
NICE guideline on depression in adults – see section 1.4.12 to 1.4.21 for information on stopping antidepressants.
NICE guideline on medicines associated with dependence or withdrawal symptoms - further recommendations on withdrawing antidepressants.
Clinical Knowledge Summary (CKS)
NICE clinical knowledge summary depression
National Polypharmacy Programme
National Polypharmacy masterclass on safely stopping antidepressants
Useful related resources from PrescQIPP:
Clinical Masterclass from August 2024
Antidepressant bulletin 330. September 2023.
https://www.prescqipp.info/our-resources/bulletins/bulletin-330-antidepressants/
Find out more about PrescQIPP here: www.prescqipp.info
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